HIV-ASSOCIATED NON HODGKIN LYMPHOMA: A CASE SERIES STUDY FROM TURKEY

Authors

  • Kayra Somay Internal Medicine Department, Koç University Medical School, İstanbul, Turkey
  • Sidar Çöpür Koç University Medical School, İstanbul, Turkey
  • Emre Osmanbaşoğlu Hematology Department, Koç University Hospital, İstanbul, Turkey
  • Helin Masyan Internal Medicine Department, Koç University Hospital, İstanbul, Turkey
  • Harun Arslan Internal Medicine Department, Koç University Hospital, İstanbul, Turkey
  • Olga Meltem Akay 5Hematology Department, Koç University Medical School, Istanbul, Turkey
  • Süda Tekin Infectious Diseases and Clinical Microbiology Department, Koç University Medical School, Istanbul, Turkey
  • Burhan Ferhanoğlu Hematology Department, Koç University Hospital, İstanbul, Turkey

DOI:

https://doi.org/10.21010/Ajid.v14i2.7

Keywords:

Human immunodeficiency virus, lymphoma, non-Hodgkin lymphoma, anti-retroviral therapy.

Abstract

Background: Human immunodeficiency virus (HIV) is a global health concern with major risks for opportunistic infections and predisposition to malignancies including Kaposi sarcoma associated with Human Herpes Virus-8 (HHV-8) and non-Hodgkin lymphoma (NHL) commonly associated with Epstein Barr Virus (EBV). Although the exact mechanisms of predisposition to certain malignancies are unclear, HIV (+) cancer patients typically have poorer prognosis.

Materials and Methods: We included all five HIV positive NHL patients receiving antiretroviral therapy (ART) and chemotherapy in our clinic and aim to determine their follow-up outcomes associated with ART.

Results: The use of ART in conjunction with chemotherapy regimens lead to better therapeutic outcome in our cases with no mortality over three years of follow-up despite high rates of poor prognostic factors and studies demonstrating 1-year survival rates of approximately 30% in HIV-associated lymphoma. No significant adverse effect has been recorded.

Conclusion: We recommend use of ART along with chemotherapy regimens in HIV positive lymphoma patients for better treatment response.

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Published

2020-07-31

How to Cite

Somay, K., Çöpür, S., Osmanbaşoğlu, E., Masyan, H., Arslan, H., Akay, O. M., Tekin, S., & Ferhanoğlu, B. (2020). HIV-ASSOCIATED NON HODGKIN LYMPHOMA: A CASE SERIES STUDY FROM TURKEY. African Journal of Infectious Diseases (AJID), 14(2), 42–47. https://doi.org/10.21010/Ajid.v14i2.7

Issue

Vol. 14 No. 2 (2020)

Section

Case Report

License

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