ANTIMALARIAL ACTIVITY OF MAMMEA AFRICANA

Authors

  • Jude Efiom Okokon Dept of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria

Keywords:

MAMMEA AFRICANA, MALARIA, ANTIPLASMODIAL

Abstract

ABSTRACT The antimalarial activity of ethanolic stembark extract of Mammea africana was studied in vivo in mice infected with Plasmodium berghei berghei during early and established infections.Mammea africana extract(30 – 90mg/kg/day) exhibited a significant (P<0.05) blood shizontocidal activity both in 4-day early infection and in established infection with a significant mean survival time comparable to that of the standard drug,chloroquine,5mg/kg/day.The stembark extract posseses a promising antiplasmodial activity which can be exploited in malaria therapy.

Author Biography

Jude Efiom Okokon, Dept of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria

Dept of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria

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Published

2006-05-29

How to Cite

Okokon, J. E. (2006). ANTIMALARIAL ACTIVITY OF MAMMEA AFRICANA. African Journal of Traditional, Complementary and Alternative Medicines, 3(4), 43–49. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/101

Issue

Vol. 3 No. 4 (2006)

Section

Research Papers

License

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