IN VITRO ANTIPLASMODIAL PROPERTIES OF FLACOURTIA FLAVESCENS WILLD.   (FLACOURTIACEAE) AND RYTIGYNIA CANTHIOIDES (BENTH.) ROBYNS (RUBIACEAE)

M. A. Djikpo-Tchibozo1; S. D. Karou; S. Sanon; F. Toukourou; C. de Souza

IN VITRO ANTIPLASMODIAL PROPERTIES OF FLACOURTIA FLAVESCENS WILLD. (FLACOURTIACEAE) AND RYTIGYNIA CANTHIOIDES (BENTH.) ROBYNS (RUBIACEAE)

Authors

M. A. Djikpo-Tchibozo1
S. D. Karou
S. Sanon
F. Toukourou
C. de Souza

Keywords:

Flacourtia flavescens, Rytigynia canthioides, Plasmodium falciparum, antiplasmodial

Abstract

The present study was conducted to investigate the in vitro antimalarial activity of Flacourtia flavescens Willd. (Flacourtiaceae) and Rytigynia canthioides (Benth.) Robyns (Rubiaceae). These two plants are used in Benin folk medicine to treat malaria and fever. Antimalarial activity was assayed on fresh clinical isolates of chloroquine resistant Plasmodium falciparum using the in vitro semi-microtest. The results revealed that the IC50 varied from 1.55 to 22.36Âµg/ml. F. flavescens hydro methanol extract was more active than R. canthioides. The study demonstrated scientific rationale behind the traditional usage of these plants, however further bioactivity guided phytochemical analyses are necessary to identify the active principles.

Author Biography

S. D. Karou

Centre de Recherche et de Formation sur les Plantes Médicinales (CERFOPLAM), Université de Lomé, Togo

Downloads

FullText.PDF

Published

2010-09-14

How to Cite

Djikpo-Tchibozo1, M. A., Karou, S. D., Sanon, S., Toukourou, F., & de Souza, C. (2010). IN VITRO ANTIPLASMODIAL PROPERTIES OF FLACOURTIA FLAVESCENS WILLD. (FLACOURTIACEAE) AND RYTIGYNIA CANTHIOIDES (BENTH.) ROBYNS (RUBIACEAE). African Journal of Traditional, Complementary and Alternative Medicines, 8(1), 66–68. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/1174

Download Citation

Issue

Vol. 8 No. 1 (2011)

Section

Research Papers

License

This license lets others distribute, remix, tweak, and build upon your work, even commercially, as long as they credit you for the original creation. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use of licensed materials. View License Deed | View Legal Code Authors can also self-archive their manuscripts immediately and enable public access from their institution's repository. This is the version that has been accepted for publication and which typically includes author-incorporated changes suggested during submission, peer review and in editor-author communications.