FLAVONOIDS FROM SUDANESE ALBIZIA ZYGIA (LEGUMINOSAE, SUBFAMILY MIMO-SOIDEAE), A PLANT WITH ANTIMALARIAL POTENCY

Authors

  • Muna Ali Abdalla
  • Hartmut Laatsch

Keywords:

Albizia zygia, Mimosoideae, flavonoids, antimalarial activity

Abstract

Three flavonoids were isolated for the first time from the Sudanese medicinal plants Albizia zygia. Compounds 1-3 were identified by interpretation of ESI mass data, 1H, 13C and 2D NMR as well as by comparison with published data as 4',7-dihydroxyflavanone (1) 3',4',7-trihydroxyflavone (2), 3-O-methylfisetin (3',4',7-trihydroxy-3-methoxyflavone, 3). All flavonoids were tested against Plasmodium falciparum, and only compound 2 showed high antimalarial activity (IC50 0.078 μg/ml).

Author Biographies

Muna Ali Abdalla

Department of Food Science and Technology, Faculty of Agriculture, University of Khartoum, Khartoum North, P.O Box 13314 Shambat, Sudan

Hartmut Laatsch

Institute of Organic and Biomolecular Chemistry, Georg-August University of Göttingen, Tammannstrasse 2, D-37077 Göttingen, Germany

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Published

2011-08-04

How to Cite

Abdalla, M. A., & Laatsch, H. (2011). FLAVONOIDS FROM SUDANESE ALBIZIA ZYGIA (LEGUMINOSAE, SUBFAMILY MIMO-SOIDEAE), A PLANT WITH ANTIMALARIAL POTENCY. African Journal of Traditional, Complementary and Alternative Medicines, 9(1), 56–58. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/1357

Issue

Vol. 9 No. 1 (2012)

Section

Research Papers

License

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