HISTOLOGICAL CHANGES IN MALE ACCESSORY REPRODUCTIVE ORGANS IN RATS EXPOSED TO CIGARETTE SMOKE AND THE PROTECTIVE EFFECT OF HONEY SUPPLEMENTATION

Authors

  • Mahaneem Mohamed
  • Siti Amrah Sulaiman
  • Hasnan Jaafar

Keywords:

honey, cigarette smoke, accessory reproductive organ, histology, male rat

Abstract

The effect of cigarette smoke (CS) on histology of male accessory reproductive organs and the possible protective effect of honey supplementation in rats were investigated in this study. Rats received distilled water, honey, CS exposure or honey plus CS exposure. Honey (1.2 g/kg body weight/day) was administered by gavage and CS exposure (3 times per day) was done in a chamber for 13 weeks. CS exposure significantly increased relative weight of epididymis and ventral prostate. There were also significantly increased number of clear cells and epithelial height of cauda epididymis as well as severe interstitial oedema and decreased epithelial height of prostate gland. However, with the supplementation of honey, these histological changes were significantly reversed suggesting the protective effect of honey against the toxic effect of CS on male accessory reproductive organs in rats.

Author Biography

Mahaneem Mohamed

Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

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Published

2012-02-01

How to Cite

Mohamed, M., Sulaiman, S. A., & Jaafar, H. (2012). HISTOLOGICAL CHANGES IN MALE ACCESSORY REPRODUCTIVE ORGANS IN RATS EXPOSED TO CIGARETTE SMOKE AND THE PROTECTIVE EFFECT OF HONEY SUPPLEMENTATION. African Journal of Traditional, Complementary and Alternative Medicines, 9(3), 329–335. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/1475

Issue

Vol. 9 No. 3 (2012)

Section

Research Papers

License

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