EVALUATION OF ANTIMICROBIAL ACTIVITY OF THE STEM BARK OF CYLICODISCUS GABUNENSIS (MIMOSACEAE)

Authors

  • Kouitcheu Mabeku Laure B
  • J. Kouam
  • Beng V. Penlap
  • Bonaventure T. Ngadjui
  • Z.T. Fomum
  • F.X. Etoa

Keywords:

Antimicrobial activity, Cylicodiscus gabunensis

Abstract

Ethyl acetate(EA) extract of the stem bark of Cylicodiscus gabunensis (CG) was analysed phytochemically and evaluated for its antimicrobial activity against 17 pathogenic species isolated from patient: Escherichia coli, Klebsiella pneumoniae, Shigella dysenteriae, Shigella flexneri, Morganella morganii, Proteus vulgaris, Proteus mirabilis , Salmonella typhi , Citrobacter freundii , Enterobacter cloacae , Enterobacter agglomerans , Staphylococcus aureus , Streptococcus feacalis , Pseudomonas aeruginosa , Bacillus cereus T, Candida albicans and Candida glabrata . Flavonoids, saponins, tannins, polyphenols, coumarins, triterpenes and/or sterols and reducing sugars were detected in the (EA) extract of CG. The best MIC and MBC values for the microorganisms sensitive to the extract were 0.00078 and 0.00315 mg/ml respectively. The greater and remarkable antimicrobial activity of the (EA) extract of CG was recorded with Staphylococcus aureus, Proteus vulgaris and Bacillus cereus T. These results provide a rationalization for the traditional use of this plant for the treatment of infections diseases.

Author Biographies

Kouitcheu Mabeku Laure B

Laboratory of the Applied Microbiology and Molecular Pharmacology, Department of Biochemistry, Faculty of Science, P. O. Box 812, University of Yaoundé I, Cameroon.

J. Kouam

Phytochemistry Laboratory, Department of Organic Chemistry, Faculty of Science, P. O. Box 812, University of Yaoundé I, Cameroon.

Beng V. Penlap

Laboratory of the Applied Microbiology and Molecular Pharmacology, Department of Biochemistry, Faculty of Science, P. O. Box 812, University of Yaoundé I, Cameroon.

Bonaventure T. Ngadjui

Phytochemistry Laboratory, Department of Organic Chemistry, Faculty of Science, P. O. Box 812, University of Yaoundé I, Cameroon.

Z.T. Fomum

Phytochemistry Laboratory, Department of Organic Chemistry, Faculty of Science, P. O. Box 812, University of Yaoundé I, Cameroon.

F.X. Etoa

Laboratory of the Applied Microbiology and Molecular Pharmacology, Department of Biochemistry, Faculty of Science, P. O. Box 812, University of Yaoundé I, Cameroon.

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Published

2006-08-28

How to Cite

Laure B, K. M., Kouam, J., Penlap, B. V., Ngadjui, B. T., Fomum, Z., & Etoa, F. (2006). EVALUATION OF ANTIMICROBIAL ACTIVITY OF THE STEM BARK OF CYLICODISCUS GABUNENSIS (MIMOSACEAE). African Journal of Traditional, Complementary and Alternative Medicines, 4(1), 87–93. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/161

Issue

Vol. 4 No. 1 (2007)

Section

Research Papers

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