A REVIEW OF THE PHARMACOLOGICAL MECHANISM OF TRADITIONAL CHINESE MEDICINE IN THE INTERVENTION OF CORONARY HEART DISEASE AND STROKE

Authors

  • Wenting Zhang
  • Kuo Gao
  • Jingwei Liu
  • Huihui Zhao
  • Juan Wang
  • Yubo Li
  • Ghulam Murtaza
  • Jianxin Chen
  • Wei Wang

Keywords:

Buyang Huanwu Decoction (BHD), Brain-Heart concurrent treatment, Pharmaceutical effect mechanism, Material basis.

Abstract

In recent years, several researches have showed that Buyang Huanwu Decoction (BHD) possesses multiple target points in the intervention of diseases, and has same treatment effects on cerebrovascular diseases and cardiovascular diseases. But, there was no full report about the mechanistic and material basis in Brain-Heart concurrent treatment. The objective of the present study was to examine the pharmacological mechanism of traditional Chinese medicine in the intervention of coronary heart disease and stroke. We combined the HIT, PubChem, David Database resource and the networked pharmacology method to ultimately find out BHD’s thirty-five potential brain-heart concurrent treatment target points, and preliminarily reveal BHD’s material basis for treatment of cerebrovascular diseases and cardiovascular diseases. Finally, the study provided new information with the guidance meanings.

Author Biography

Wenting Zhang

Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chao Yang District, Beijing 100029 Peoples Republic of China.

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Published

2013-09-24

How to Cite

Zhang, W., Gao, K., Liu, J., Zhao, H., Wang, J., Li, Y., Murtaza, G., Chen, J., & Wang, W. (2013). A REVIEW OF THE PHARMACOLOGICAL MECHANISM OF TRADITIONAL CHINESE MEDICINE IN THE INTERVENTION OF CORONARY HEART DISEASE AND STROKE. African Journal of Traditional, Complementary and Alternative Medicines, 10(6), 532–537. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/2123

Issue

Vol. 10 No. 6 (2013)

Section

Review

License

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