EXPERIMENTAL STUDY ON THE OPTIMIZATION OF EXTRACTION PROCESS OF GARLIC OIL AND ITS ANTIBACTERIAL EFFECTS

Authors

  • Yajie Guo

Keywords:

garlic oil, CO2, supercritical extraction, Staphylococcus aureus, Escherichia coli, Bacillus subtilis

Abstract

Background: Garlic oil which is the main active constituent of garlic has a wide range of pharmacological activities, and a broad antibacterial spectrum. It also has a strong anti-cancer activity, and can significantly inhibit a variety of tumors such as liver cancer, gastric cancer and colon cancer. The objective is to study the extraction process of garlic oil and its antibacterial effects. Materials and Methods: CO2 Supercritical extraction was used to investigate the optimal processing conditions for garlic oil extraction; filter paper test and suspension dilution test were applied to determine the bacteriostatic action of garlic oil. Results: In the CO2 supercritical extraction experiment, factors influencing the yield of garlic oil were: extraction pressure > extraction temperature > extraction time in descending order. Range analysis showed that the optimal experimental conditions for CO2 supercritical extraction of garlic oil were extraction pressure of 15 Mpa, temperature of 40 ℃, and duration of 1 h. Different concentrations of garlic oil could all inhibit the growth of Staphylococcus aureus, Escherichia coli and Bacillus subtilis, suggesting that garlic oil has an antibacterial effect. Conclusion: The optimal experimental conditions for CO2 supercritical extraction of garlic oil were: extraction pressure of 15 Mpa, temperature of 40 ℃, and duration of 1 h; garlic oil has an antibacterial effect.

Author Biography

Yajie Guo

College of Materials and Chemistry and Chemical Engineering, Chengdu University of Technology, Chengdu, Sichuan 610059, China

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Published

2014-01-23

How to Cite

Guo, Y. (2014). EXPERIMENTAL STUDY ON THE OPTIMIZATION OF EXTRACTION PROCESS OF GARLIC OIL AND ITS ANTIBACTERIAL EFFECTS. African Journal of Traditional, Complementary and Alternative Medicines, 11(2), 411–414. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/2348

Issue

Vol. 11 No. 2 (2014)

Section

Research Papers

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