ANTIMALARIAL ACTIVITY OF SWARTZIA MADAGASCARIENSIS DESV. (LEGUMINOSAE), COMBRETUM GLUTINOSUM GUILL. & PERR. (COMBRETACEAE) AND TINOSPORA BAKIS MIERS. (MENISPERMACEAE), BURKINA FASO MEDICINAL PLANTS

Authors

  • Y. Ouattara
  • S Sanon
  • Y. Traoré
  • V. Mahiou
  • N Azas
  • L. Sawadogo

Keywords:

Antimalarial activity, Swartzia madagascariensis, Combretum glutinosum, Tinospora bakis.

Abstract

Swartzia madagascariensis, Combretum glutinosum and Tinospora bakis are three plants of the folk medicine used by healers in Burkina Faso for the treatment of malaria. A scientific validation of this utilization was not previously made. Aqueous, methanol, hydromethanol extracts from the roots bark of S. madagascariensis, methanol and hydromethanol extracts from the leaves of C. glutinosum and aqueous and alkaloidal extracts from the roots of T. bakis were also made and their antimalarial activity was screened against Plasmodium falciparum chloroquine-resistant strain W2 in vitro. The screening showed that the methanol and hydromethanol extracts of Swartzia madagascariensis, hydromethanol extracts of Combretum glutinosum and alkaloidal extracts of Tinospora bakis were active (5µg/ml < IC50 < 50 µg/ml).

Author Biographies

Y. Ouattara

Laboratory of Animal Physiology, UFR-SVT, University of Ouagadougou, Burkina Faso, 03 BP 7021 Ouagadougou 03

S Sanon

National Center of Research and of Formation on Malaria, Ouagadougou, Burkina Faso

Y. Traoré

Laboratory of Immunology and Biochemistry, CRSBAN, UFR-SVT, University of Ouagadougou

V. Mahiou

Laboratory of Pharmacognosy, Faculty of Pharmacy, University of the Mediterranee, 27 Bd Jean Moulin, 13385 Marseilles Cedex 5, France

N Azas

Laboratory of Parasitology, Faculty of Pharmacy, University of the Mediterranee, 27 Bd Jean Moulin, 13385 Marseilles Cedex 5, France

L. Sawadogo

Laboratory of Animal Physiology, UFR-SVT, University of Ouagadougou, Burkina Faso, 03 BP 7021 Ouagadougou 03

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Published

2006-01-12

How to Cite

Ouattara, Y., Sanon, S., Traoré, Y., Mahiou, V., Azas, N., & Sawadogo, L. (2006). ANTIMALARIAL ACTIVITY OF SWARTZIA MADAGASCARIENSIS DESV. (LEGUMINOSAE), COMBRETUM GLUTINOSUM GUILL. & PERR. (COMBRETACEAE) AND TINOSPORA BAKIS MIERS. (MENISPERMACEAE), BURKINA FASO MEDICINAL PLANTS. African Journal of Traditional, Complementary and Alternative Medicines, 3(1), 75–81. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/8

Issue

Vol. 3 No. 1 (2006)

Section

Research Papers

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