EFFECT OF PICRORHIZA KURROA ROOTS ON BLOOD GLUCOSE LEVEL ON ALLOXAN INDUCED DIABETIC RATS

Authors

  • P. Hurakadle
  • M. Patil
  • S. Jalalpure
  • F. Manvi

Abstract

The polar and nonpolar solvent extracts of Picrorhiza kurroa roots were screened at the oral dose of 250 mg/kg body weight for antidiabetic activity using alloxan induced diabetic rats on prolonged treatment studies. Petroleum ether, alcoholic and aqueous extracts of roots of Picrorhiza kurroa showed significant (p<0.01) antidiabetic results with prolonged treatment studies. The extracts contained alkaloids, flavonoids and glycosides. The results were comparable with the standard drug glibenclamide and a standard marketed herbal product, which revealed that sterols in petroleum ether extract, flavonoids, alkaloids and glycosides in alcoholic and aqueous extracts were responsible for antidiabetic activity.

Author Biography

P. Hurakadle

Department of Pharmacognost and Phytochemistry, KLES COllege, Belgaum-590 010, Karnataka, India, pramodhj75@rediffmail.com

Published

2009-05-04

How to Cite

Hurakadle, P., Patil, M., Jalalpure, S., & Manvi, F. (2009). EFFECT OF PICRORHIZA KURROA ROOTS ON BLOOD GLUCOSE LEVEL ON ALLOXAN INDUCED DIABETIC RATS. African Journal of Traditional, Complementary and Alternative Medicines, 6, 439. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/860

Issue

ABSTRACTS OF THE WORLD CONGRESS ON MEDICINAL AND AROMATIC PLANTS, CAPE TOWN NOVEMBER 2008

Section

Conference Abstracts

License

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