HBV INFECTION AMONG HIV-INFECTED COHORT AND HIV-NEGATIVE HOSPITAL ATTENDEES IN SOUTH WESTERN NIGERIA

Authors

  • Olubusuyi Moses Adewumi University of Ibadan
  • Emmanuel Donbraye Obafemi Awolowo University
  • Folorunso Waidi Sule Osun State University
  • Olarinde Olaniran Obafemi Awolowo University

Keywords:

ART, HBV, HIV, Nigeria, Dual positivity

Abstract

Background: Prevalence, association and probable mode of acquisition of HBV and HIV dual infections have not been fully explored. Thus, HBV intervention plan and services are sometimes exclusively targeted towards HIV-infected population. We investigated HBV infection among HIV-infected cohort in comparison with HIV-negative hospital attendees to ascertain dual infectivity pattern; thereby encouraging appropriate allotment of intervention services. Materials and Methods: A total of 349 (M=141; F=208; Mean=33.98 years; Range= 0.33-80 years) plasma specimens from two virus diagnostic laboratories in south-western Nigeria were analysed. These include 182 HIV-positive and 167 HIV-negative specimens from ART and GDV laboratories respectively. The specimens were initially screened for detectable HIV antigen/antibody, and subsequently HBsAg by ELISA technique. Results: Overall, HBsAg was detected in 20.92% (95% CI: 16.65-25.19%) of the patients. Also, 24.82% (95% CI: 17.69-31.95%) and 18.27% (95% CI: 13.02-23.52%) HBsAg positivity was recorded for males and females respectively. CHI square analysis showed no association (P=0.14) between gender and prevalence of HBsAg. Similarly, comparison of prevalence of HBsAg by age groups shows no significant difference (P=0.24). Overall, no significant difference (P=0.59) was observed in the prevalence of HBsAg among the HIV-infected cohort and HIV-negative hospital attendees. Conclusions: Results of the study confirm endemicity and comparable rates of HBV infection independent of HIV-status.

Author Biographies

Olubusuyi Moses Adewumi, University of Ibadan

Department of Virology Lecturer I

Emmanuel Donbraye, Obafemi Awolowo University

Department of Medical Microbiology and Parasitology Lecturer I

Folorunso Waidi Sule, Osun State University

Department of Biological Sciences Lecturer I

Olarinde Olaniran, Obafemi Awolowo University

Department of Medical Microbiology and Parasitology Medical Laboratory Scientist

Downloads

Published

2014-08-20

How to Cite

Adewumi, O. M., Donbraye, E., Sule, F. W., & Olaniran, O. (2014). HBV INFECTION AMONG HIV-INFECTED COHORT AND HIV-NEGATIVE HOSPITAL ATTENDEES IN SOUTH WESTERN NIGERIA. African Journal of Infectious Diseases (AJID), 9(1), 14–17. Retrieved from https://athmsi.org/journals/index.php/AJID/article/view/2465

Issue

Section

Articles

Most read articles by the same author(s)