STUDY ON IN VITRO ANTI-TUMOR ACTIVITY OF BIDENS BIPINNATA L. EXTRACT

Authors

  • Qing-Hui Yang
  • Jun Yang
  • Guo-Ze Liu
  • Lei Wang
  • Tie-Chui Zhu
  • Hai-Li Gao
  • Xiao-Ge Kou

Keywords:

Bidens Bipinnata L., cell culture, anti-tumor, MTT

Abstract

We studied the in vitro anti-tumor activity of Bidens Bipinnata L. extract. MTT assay was used to investigate the inhibitory effect of different concentrations of the extracts on human hepatocellular carcinoma (HepG2) cell lines and human cervical carcinoma (Hela) cell lines, and the IC50 values were calculated. The Bidens Bipinnata L. extract had different degrees of inhibitory effects on these two cells, and when exposure time was 48 h, the inhibition rate reached its peak, with IC50 values of 14.80 μg/mL and 13.50 μg/mL respectively. The Bidens Bipinnata L. extract had a good inhibitory effect on human HepG2 cell lines and Hela cell lines, and thus has certain development prospects.

Author Biographies

Qing-Hui Yang

Department of Oncology, First Affiliated Hospital of Xinxiang Medical University Weihui, 453100, Henan, China.

Xiao-Ge Kou

Department of Oncology, First Affiliated Hospital of Xinxiang Medical University Weihui, 453100, Henan, China.

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Published

2013-03-19

How to Cite

Yang, Q.-H., Yang, J., Liu, G.-Z., Wang, L., Zhu, T.-C., Gao, H.-L., & Kou, X.-G. (2013). STUDY ON IN VITRO ANTI-TUMOR ACTIVITY OF BIDENS BIPINNATA L. EXTRACT. African Journal of Traditional, Complementary and Alternative Medicines, 10(3), 543–549. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/1805

Issue

Vol. 10 No. 3 (2013)

Section

Research Papers

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