STUDY ON IN-VIVO ANTI-TUMOR ACTIVITY OF VERBENA OFFICINALIS EXTRACT

Authors

  • Wei-Zheng Kou
  • Jun Jun Yang
  • Qing-Hui Yang
  • Ying Wang
  • Zhi-Fen Wang
  • Su-Ling Xu
  • Jing Liu

Keywords:

Verbena officinalis extract, H22 mouse, tumor inhibition, immune function

Abstract

We investigated the anti-tumor effects of Verbena officinalis extract on H22 tumor-bearing mice and its effect on immune function. Mice model of H22 solid tumor was established, the mice were divided into five groups and administered the extract, later, tumors were removed and inhibition rates were calculated; spleens were removed and spleen indices were calculated, and the sheep red blood cell-delayed-type hypersensitivity (SRBC-DTH) and the serum hemolysin level were determined. The Verbena officinalis extract had anti-tumor effect, with the inhibition rate reaching 38.78%, it also increased the spleen index to a certain extent, in addition, the changes in DTA and HA were not obvious compared with the model group. The Verbena officinalis extract had in vivo anti-tumor effect, while causing no damage on the immune function.

Author Biography

Wei-Zheng Kou

Department of Oncology, First Affiliated Hospital of Xinxiang Medical University Weihui 453100, Henan, China

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Published

2013-03-18

How to Cite

Kou, W.-Z., Jun Yang, J., Yang, Q.-H., Wang, Y., Wang, Z.-F., Xu, S.-L., & Liu, J. (2013). STUDY ON IN-VIVO ANTI-TUMOR ACTIVITY OF VERBENA OFFICINALIS EXTRACT. African Journal of Traditional, Complementary and Alternative Medicines, 10(3), 512a–517. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/1801

Issue

Vol. 10 No. 3 (2013)

Section

Research Papers

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