AN EXPERIMENTAL STUDY ON THE ANTI-EHRLICH ASCITES CARCINOMA EFFECT OF PURIFIED TOAD VENOM EXTRACT

Authors

  • Ying Wang

Keywords:

Purified toad venom extract, anti-Ehrlich ascites carcinoma, ascites inhibition rate

Abstract

The objective of this paper was to study the anti-Ehrlich ascites carcinoma effect of purified toad venom extract and its mechanism. Mouse model of Ehrlich ascites carcinoma was established with cisplatin as the control to observe the inhibitory effect of purified toad venom extract on malignant peritoneal effusion in mice. The results showed that compared with the control group, ascites volume, number of tumour cells and tumour cell viability decreased and ascites inhibition rate reached over 50% in each treatment group, and with the increase of the dose, incidence of ascites showed a downward trend. The number of tumour cells in ascites and tumour cell viability in the purified toad venom high-dose group were lower than those of the cisplatin group. Compared with the model group, survival time was prolonged in varying degrees in the purified toad venom groups and cisplatin group. The study concluded that purified extract of toad venom has an anti-Ehrlich ascites carcinoma effect.

Author Biography

Ying Wang

Pharmacy Admixture Services, Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China

Downloads

Published

2013-09-24

How to Cite

Wang, Y. (2013). AN EXPERIMENTAL STUDY ON THE ANTI-EHRLICH ASCITES CARCINOMA EFFECT OF PURIFIED TOAD VENOM EXTRACT. African Journal of Traditional, Complementary and Alternative Medicines, 10(6), 547–550. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/2126

Issue

Vol. 10 No. 6 (2013)

Section

Research Papers

License

Copyright: Creative Commons Attribution CC.

This license lets others distribute, remix, tweak, and build upon your work, even commercially, as long as they credit you for the original creation. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use of licensed materials. View License Deed | View Legal Code Authors can also self-archive their manuscripts immediately and enable public access from their institution's repository. This is the version that has been accepted for publication and which typically includes author-incorporated changes suggested during submission, peer review and in editor-author communications.